We recommend that you apply either Frontline or Advantix to your dog on a monthly basis, year around. Ticks are most active in the cooler weather while fleas thrive in the hot summer months. Application should be made directly to the skin in multiple sites on the back of the neck, shoulders and on the back above the tail. Application to the fur does not help! Avoid bathing your dog within 48 hours of application (either before or after).